Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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901
Tocris Bioscience™ dTAG-47
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Degrades mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation
902
Tocris Bioscience™ TDI 11861
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Soluble adenylyl cyclase inhibitor
903
Tocris Bioscience™ NSC 668036
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Wnt signaling inhibitor; binds the PDZ domain of the Dishevelled (Dvl) protein
| CAS | 144678-63-7 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Color | White |
| Solubility | Soluble to 100mM in DMSO and to 100mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanine-(1S)-1-carboxy-2-methylpropyl ester |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H36N2O9 |
| Formula Weight | 460.52 |
904
Tocris Bioscience™ (S)-3,4-DCPG
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CAS: 201730-11-2 Molecular Formula: C10H9NO6
| CAS | 201730-11-2 |
|---|---|
| Molecular Formula | C10H9NO6 |
905
Tocris Bioscience™ SPRi 3
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Potent sepiapterin reductase (SPR) inhibitor (IC50 = 53 - 74 nM for human SPR); attenuates proliferation of CD4+ T cells
| CAS | 1292285-54-1 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[2-(5-Hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H18N2O3 |
| Formula Weight | 262.3 |
906
Tocris Bioscience™ SB 297006
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Potent and selective CCR3 antagonist
| Inhibitors | SB 297006 |
|---|---|
| Product Type | SB 297006 |
| Molecular Weight (g/mol) | 342.35 |
| Purity | >99% |
907
Tocris Bioscience™ Auxinole
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Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system
| Target | Molecular Glues |
|---|---|
| CAS | 86445-22-9 |
| Purity | 98% |
| Chemical Name or Material | α-[2-(2,4-Dimethylphenyl)-2-oxoethyl]-1H-indole-3-acetic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H19NO3 |
908
Tocris Bioscience™ (±)-trans-ACPD
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CAS: 67684-64-4 Molecular Formula: C7H11NO4
| CAS | 67684-64-4 |
|---|---|
| Molecular Formula | C7H11NO4 |
909
Tocris Bioscience™ Kenpaullone
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CAS: 142273-20-9 Molecular Formula: C16H11BrN2O
| CAS | 142273-20-9 |
|---|---|
| Molecular Formula | C16H11BrN2O |
910
Tocris Bioscience™ IOX 2
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CAS: 931398-72-0 Molecular Formula: C19H16N2O5
| CAS | 931398-72-0 |
|---|---|
| Molecular Formula | C19H16N2O5 |
911
Tocris Bioscience™ Rimcazole dihydrochloride
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CAS: 75859-03-9 Molecular Formula: C21H29Cl2N3
| CAS | 75859-03-9 |
|---|---|
| Molecular Formula | C21H29Cl2N3 |
912
Tocris Bioscience™ MD15
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Negative control for MD13 (Cat. No. 7503)
913
Tocris Bioscience™ AZD 1480
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Potent and selective JAK2 inhibitor; antiangiogenic
914
Tocris Bioscience™ PI 103 hydrochloride
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CAS: 371935-79-4 Molecular Formula: C19H17ClN4O3
| CAS | 371935-79-4 |
|---|---|
| Molecular Formula | C19H17ClN4O3 |
915
Tocris Bioscience™ SB 222200
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CAS: 174635-69-9 Molecular Formula: C26H24N2O
| CAS | 174635-69-9 |
|---|---|
| Molecular Formula | C26H24N2O |